For biopsy submission, with particular reference to skin tumours, the mass should be submitted whole and intact, in adequate fixative as described above. This will allow assessment of excision margins. If very large, a representative sample to include an edge can be submitted. The history in this case must clearly indicate that it is a representative sample since full assessment of excision margins may not be possible. The submission form should include age, breed, sex, site of removal and a clinical history to include any treatment.